ECMO support for COVID-19: a balancing act

A balancing act for autophagin.

Autophagy is a tightly regulated catabolic process whereby cells degrade their constituents to dispose of unwanted cytoplasmic elements and recycle nutrients for cellular remodeling. Studies of autophagy in mammals have elicited substantial interest because it is linked to a range of physiologic and pathologic states. In this issue of the JCI, Mariño et al. uncover a role for autophagy in a bal...

A PKGarious Balancing Act

The pathologically hypertrophied and failing heart is a battlefield in a war that would make even George Lucas proud. On the one side, you have hemodynamic, neurohormonal, morphological, and cellular/molecular dark forces urging the ventricle toward decompensation and ultimate demise. On the other, Jedi signaling cascades try valiantly to stave off the impending disaster. Alas, unlike the movie...

Balancing act for elderly myeloma.

The wandering of families with schizophrenia patient in a challenging support system and covid 19 crisis

Introduction: schizophrenia is a chronic condition that leads to debilitating consequences, is associated numerous challenges. So families need long-term psychosocial support. Methods: the study was performed by interpretive descriptive method. Using purposive sampling, 30 participants participated in the study. Data were collected through individual interviews and coded, codes with similar the...

History in a Crisis — Lessons for Covid-19

Writing in the heady days of new antibiotics and immunizations, esteemed microbiologists Macfarlane Burnet and David White predicted in 1972 that “the most likely forecast about the future of infectious diseases is that it will be very dull.” When asked to explain past events, historians are quick to assert the importance of context. If you want to understand how or why something happened, you ...